Over 20 million exosomes. Pore elasticity that lasts 7 days.

The Medicube Zero One Day Exosome Shot Pore Ampoule 25000 is the most powerful pore-tightening ampoule in the Medicube range — containing over 20 million exosomes and 25,000PPM exosome concentration for precise, deep pore-tightening action. A single weekly use maintains pore elasticity for 7 days, making it the ultimate high-performance treatment for those who want clinical-grade pore care at home.

Key Benefits

• 25,000PPM exosome concentration — the highest in the Medicube range
• Over 20 million exosomes per ampoule for maximum pore-tightening precision
• Maintains pore elasticity for 7 days from a single weekly application
• Penetrates 25x smaller than a pore for direct, deep delivery
• Gluconolactone and betaine salicylate gently exfoliate and clear pores
• Ceramide NP and peptide complex support barrier health post-treatment

Hero Ingredients

• Exosomes 25,000PPM (20M+) — highest-concentration exosome complex that tightens sagging pores and restores elasticity deep within the skin
• Lactobacillus Extracellular Vesicles — probiotic-derived vesicles that support skin balance alongside the exosome complex
• Gluconolactone (PHA) — gently exfoliates and clears pores with minimal irritation
• Ceramide NP + Peptide Complex — maintain barrier health and support firmness after treatment

How to Use

After cleansing in the evening, once every 7 days, apply an appropriate amount to bare skin avoiding the eye and lip areas. Gently press until absorbed, then apply a moisturiser to finish. Read all directions carefully before first use.

Ingredients

Purified Water, Glycereth-26, Dipropylene Glycol, Butylene Glycol, Caprylic/Capric Triglyceride, Niacinamide, Calcium Aluminum Borosilicate, Hydrolyzed Sponge, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, 1,2-Hexanediol, Caprylyl Glycol, Isohexadecane, Glycerin, Polysorbate 80, Carbomer, Tromethamine, Panthenol, Ethylhexylglycerin, Adenosine, Sorbitan Oleate, Sorbitan Isostearate, Polysorbate 60, Disodium EDTA, Lactobacillus Extracellular Vesicles, Knotweed Extract, Evening Primrose Extract, Elm Root Extract, Pine Leaf Extract, Kudzu Root Extract, Red Cinchona Bark Extract, Gluconolactone, Betaine Salicylate, Citric Acid, Milk Exosome, Manuka Leaf Extract, Hydrogenated Lecithin, Polyglyceryl-10 Laurate, Ceramide NP, Acetyl Tetrapeptide-5, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-5